Hyperpolarized singlet NMR on a small animal imaging system
نویسندگان
چکیده
منابع مشابه
Hyperpolarized singlet NMR on a small animal imaging system.
Nuclear spin hyperpolarization makes a significant advance toward overcoming the sensitivity limitations of in vivo magnetic resonance imaging, particularly in the case of low-gamma nuclei. The sensitivity may be improved further by storing the hyperpolarization in slowly relaxing singlet populations of spin-1/2 pairs. Here, we report hyperpolarized (13) C spin order transferred into and retrie...
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High-sensitivity nuclear magnetic resonance (NMR) of gaseous atoms realized by using a hyperpolarization technique is an attractive research tool used in a wide range of areas, such as physics, chemistry, material science and biomedical imaging. One of the most promising applications of this technology is the use as a noninvasive diagnostic tool for pulmonary diseases, where hyperpolarized (HP)...
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Introduction Hyperpolarized (HP) gas MRI in small animals is challenging and generally requires a dedicated ventilator system. Moreover, the use of expensive rare isotopes such as He and Xe make it desirable to minimize cost by recycling these gases after they have been used for imaging. We present a constantvolume ventilator that offers precise control of gas delivery, permits highresolution i...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2012
ISSN: 0740-3194
DOI: 10.1002/mrm.24430